CDA-M52W3
Mouse CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free (MALS verified)
Cannot supply to this region.
- SKU:
- CDA-M52W3
- Physical State:
- Powder
- Molecular Weight:
- 24.9 kDa & 21.9 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- CD8 alpha & beta
- Species:
- Mouse
- Uniprot:
- P01731-1, P10300
- Synonyms:
- Cd8b;Ly-;Ly-3;Ly-C;lymphocyte antigen 3;Lyt-;Lyt-3;T-cell membrane glycoprotein Ly-3;T-cell surface glycoprotein CD8 beta chain;T-cell surface glycoprotein Lyt-2;T-cell surface glycoprotein Lyt-3
- Extra Details:
- The CD8A AlphaB Beta heterodimer is a key cell surface co-receptor on cytotoxic T lymphocytes. It binds to MHC class I molecules on antigen-presenting cells, stabilizing the interaction between the T-cell receptor (TCR) and the peptide-MHC complex. This binding is essential for T-cell activation, positive selection in the thymus, and the effector function of mature CD8+ T cells. The B Beta-chain (CD8B Beta) modulates the affinity of the interaction, contributes to signal transduction, and promotes the stable surface expression of the heterodimer.
- Shipping Conditions:
- Ambient