Alexa Fluor[TM] 488-Labeled Human CD8 alpha Protein, His Tag

Cannot supply to this region.

SKU:: CDA-HA2H6
Physical State:: Powder
Molecular Weight:: 19.5 kDa
Storage Conditions:: Please refer to datasheet
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: CD8 alpha
Species:: Human
Uniprot:: P01732-1
Synonyms:: T-lymphocyte differentiation antigen T8/Leu-2
Extra Details:: Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.