Biotinylated Human CD8 alpha / CD8A Protein, His,Avitag[TM] (MALS verified)

Cannot supply to this region.

SKU:: CDA-H82E3
Additional Names:: CD8|CD8A|Leu2|MAL|p32
Physical State:: Powder
Molecular Weight:: 21.2 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
ABP:: No Import Docs
Buffer:: PBS
Immunogen:: CD8 alpha
Species:: Human
Uniprot:: P01732-1
Synonyms:: T-lymphocyte differentiation antigen T8/Leu-2
Extra Details:: Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.