Human CD300a / LMIR1 Protein, His Tag, low endotoxin (MALS verified)

Cannot supply to this region.

SKU:: CDA-H52H5
Physical State:: Powder
Molecular Weight:: 14.4 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: CD300a
Species:: Human
Uniprot:: Q9UGN4-1
Synonyms:: CD300 antigen-like family member A;CMRF-35-H9;CMRF35-H;Immunoglobulin superfamily member 12;Inhibitory receptor protein 60;IRC1/IRC2;NK inhibitory receptor
Extra Details:: CD300a, expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.