Biotinylated Cynomolgus CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His,Avitag[TM]&Tag Free (MALS verified)

Cannot supply to this region.

SKU:: CDA-C82W3
Physical State:: Powder
Molecular Weight:: 25.4 kDa & 21.1 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: CD8 alpha & beta
Species:: Non-human Primate
Extra Details:: Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.