Biotinylated Human CD209 / DC-SIGN Protein, Avitag[TM],His Tag

Cannot supply to this region.

SKU:: CD9-H82Q3
Physical State:: Powder
Molecular Weight:: 43.0 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: CD209
Species:: Human
Uniprot:: Q9NNX6-1
Synonyms:: C-type lectin domain family 4 member L;Dendritic cell-specific ICAM-3-grabbing non-integrin 1
Extra Details:: CD209 is also known as CLEC4L, DC-SIGN and CD209 antigen. Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells.