CD9-H5256
Human CD109 / CPAMD7 protein, Fc Tag
Cannot supply to this region.
- SKU:
- CD9-H5256
- Physical State:
- Powder
- Molecular Weight:
- 166.2 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
- Immunogen:
- CD109
- Species:
- Human
- Uniprot:
- Q6YHK3-1
- Synonyms:
- 150 kDa TGF-beta-1-binding protein;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7;p180;Platelet-specific Gov antigen;r150
- Extra Details:
- CD109 is a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. CD109 is expressed in many malignant tumors, including various squamous cell carcinomas and adenocarcinomas, and plays a role as a multifunctional coreceptor.CD109 reportedly associates with transforming growth factor (TGF)-B Beta receptors and negatively regulates TGF-B Beta signaling in keratinocytes. Additionally, CD109 is potentially related to signal transducer and activator of transcription-3 signaling and aberrant cell proliferation.
- Shipping Conditions:
- Ambient