CD1-H5256
Human IL-3 R Beta / CD131 Protein, Fc Tag (MALS verified)
Cannot supply to this region.
- SKU:
- CD1-H5256
- Additional Names:
- CD131|Common beta Chain|IL-3 R Beta
- Physical State:
- Powder
- Molecular Weight:
- 75.1 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
- Immunogen:
- CD131
- Species:
- Human
- Uniprot:
- P32927-1
- Synonyms:
- CDw131;GM-CSF/IL-3/IL-5 receptor common beta subunit
- Extra Details:
- CD131- the common B Beta Subunit, is a member of the type 1 cytokine receptor family. There are three major classes of heteroreceptor complexes, where the receptor complex utilises a common shared receptor subunit as a signal-transducing chain along with a cytokine specific subunit. These three classes include those which use gp130, those which use G Gammac and those which use the common B Beta subunit, B Betac(CD131). CD131 is shared by three of the "four-helical bundle" family of cytokines; IL-3, IL-5 and GM-CSF, and forms a receptor complex along with a cytokine specific A Alpha chain for each of these cytokines.Moreover, even though each of these cytokines have their own specific A Alpha subunit, the co-utilisation of CD131 suggests a common intra-cellular process of both unique and/or overlapping activities on expressing cells.
- Shipping Conditions:
- Ambient