Human CCR8 Full Length Protein, Flag,His Tag (Nanodisc-pro)

Cannot supply to this region.

SKU:: CC8-H52D3
Physical State:: Liquid
Molecular Weight:: 57.1 kda
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM HEPES, 150 mM NaCl, pH7.5
Immunogen:: CCR8
Species:: Human
Uniprot:: P51685-1
Synonyms:: CC chemokine receptor CHEMR1;Chemokine receptor-like 1;CMKBRL2;GPR-CY6;TER1
Extra Details:: This entry represents CC chemokine receptor 8 (CCR8), which it is expressed predominantly in lymphoid tissues and has also been found in glomerular podocytes and human umbilical vein endothelial cells (HUVECs). CCR8 is associated with Th2 lymphocytes, which are critical for allergy, and has a role in lymphocyte activation, migration, proliferation and differentiation and in allergic diseases. CCR8 binds to CCL1 (also known as I-309) and to CCL16 (also known as liver expressed chemokine). It also exhibits a high affinity for three chemokines of viral origin: vMIP-I, vMIP-II and vMCC-I.