CC5-M52D9
Mouse CCR5 Protein, Flag,His Tag (Detergent)
Cannot supply to this region.
- SKU:
- CC5-M52D9
- Physical State:
- Liquid
- Molecular Weight:
- 44.1 kda
- Storage Conditions:
- -70[o]C
- Supplier:
- ACRO Biosystems
- ABP:
- No Import Docs
- Buffer:
- 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
- Immunogen:
- CCR5
- Species:
- Mouse
- Uniprot:
- P51682
- Synonyms:
- AM4-7;C-C chemokine receptor type 5;C-C CKR-5;CC-CKR-5;CCR-5;CD195;chemokine (C-C) receptor 5;Cmkbr;Cmkbr5;MIP-1 alpha receptor
- Extra Details:
- A chemokine receptor acting as the primary co-receptor for HIV-1 entry into host cells. Clinically validated by the FDA-approved inhibitor Maraviroc, CCR5 also regulates immune cell trafficking. Its blockade is being explored in oncology to reprogram the tumor microenvironment and enhance responses to checkpoint inhibitors.
- Shipping Conditions:
- Dry Ice