Human CCR2 Full Length Protein, Flag,His Tag (Detergent)

Cannot supply to this region.

SKU:: CC2-H52D4
Physical State:: Liquid
Molecular Weight:: 45.3 kDa
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Immunogen:: CCR2
Species:: Human
Uniprot:: P41597-1
Synonyms:: Monocyte chemoattractant protein 1 receptor
Extra Details:: The primary receptor for CCL2 (MCP-1), a major chemokine driving monocyte egress from bone marrow and recruitment to inflamed tissues. The CCR2-CCL2 axis promotes tumor-associated macrophage (TAM) accumulation and fibrosis. Antagonists aim to reprogram the immunosuppressive tumor stroma and treat inflammatory diseases.