Human Cathepsin D Protein, Tag Free (Pro-form)

Cannot supply to this region.

SKU:: CAD-H5213
Physical State:: Liquid
Molecular Weight:: 42.6 kDa
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 12.5 mM MES, 75 mM NaCl, pH6.5
Immunogen:: Cathepsin D
Species:: Human
Uniprot:: P07339-1
Extra Details:: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]