Biotinylated Mouse Cadherin-17 / CDH17 Protein, His,Avitag[TM] (MALS verified)

Cannot supply to this region.

SKU:: CA7-M82E7
Physical State:: Powder
Molecular Weight:: 87.9 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 20 mM Tris, 150 mM NaCl, pH8.0
Immunogen:: Cadherin-17
Species:: Mouse
Uniprot:: Q9R100-1
Synonyms:: BILL-cadherin;Liver-intestine cadherin;P130
Extra Details:: Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.