Human BTN2A1 / Butyrophilin Protein, His Tag, low endotoxin (MALS verified)

Cannot supply to this region.

SKU:: BT1-H52H6
Additional Names:: BK14H9.1|BT2.1|BTF1|BTF1BT2.1butyrophilin BTF1|BTN2A1|butyrophilin|butyrophilin subfamily 2 member A1|DJ3E1.1|FLJ36567|member A1|subfamily 2
Physical State:: Powder
Molecular Weight:: 26.4 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: BTN2A1
Species:: Human
Uniprot:: Q7KYR7-2
Extra Details:: Duplication events have led to three paralogues of BTN2A in primates: BTN2A1, BTN2A2, and BTN2A3. In humans, only BTN2A1 has been functionally characterised; it has been detected on epithelial cells and leukocytes, and identified as a novel ligand of dendritic cell-specific ICAM-3 grabbing nonintegrin (DCSIGN), a C-type lectin receptor that acts as an internalization receptor for HIV-1, HCV, and other pathogens. BTN2A2 mRNA has been shown to be expressed in circulating human immune cells.