Biotinylated Human BLAME / SLAMF8 Protein, His,Avitag[TM]

Cannot supply to this region.

SKU:: BLE-H82E4
Additional Names:: BLAME|CD353|SLAMF8
Physical State:: Powder
Molecular Weight:: 27.1 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
ABP:: No Import Docs
Buffer:: 50 mM Sodium Citrate, 150 mM NaCl, pH5.5
Immunogen:: BLAME
Species:: Human
Uniprot:: Q9P0V8-1
Synonyms:: B-lymphocyte activator macrophage expressed;BCM-like membrane protein
Extra Details:: BLAME (B-lymphocyte activator macrophage expressed) is also known as SLAM family member 8(SLAMF8), CD353. BLAME is a cell surface receptor that is expressed upon activation of macrophages (MF Phis) by IFN-G Gamma or bacteria, is a negative regulator of ROS in response to Gram+ and Gram- bacteria. May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor. SLAMF8 is a costimulatory molecule that affects the activation of macrophages in inflammation and in immunosuppression and inflammation response to glioma cells could aid immunotherapy for glioma.