BC1-H513A
Human Bcl-x / BCL2L1 Protein, GST Tag
Cannot supply to this region.
- SKU:
- BC1-H513A
- Additional Names:
- Bcl-X|Bcl-XL|bcl-xS|Bcl2-L-1|BCL2L|BCL2L1|BCLX|BCLXL|BCLXS|S
- Physical State:
- Powder
- Molecular Weight:
- 50.6 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- ABP:
- No Import Docs
- Buffer:
- 20 mM Tris, 100 mM NaCl, 10 mM GSH, pH7.5
- Immunogen:
- Bcl-x
- Species:
- Human
- Extra Details:
- Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
- Shipping Conditions:
- Ambient