B77-H52H6
Human B7-H7 / HHLA2 Protein, His Tag, low endotoxin (MALS verified)
Cannot supply to this region.
- SKU:
- B77-H52H6
- Additional Names:
- B7 Homolog 7|B7-H7|HHLA2
- Physical State:
- Powder
- Molecular Weight:
- 39.0 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- B7-H7
- Species:
- Human
- Uniprot:
- Q9UM44-1
- Synonyms:
- Human endogenous retrovirus-H long terminal repeat-associating protein 2
- Extra Details:
- B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
- Shipping Conditions:
- Ambient