Human B7-H5 / Gi24 / VISTA Protein, Fc Tag

Cannot supply to this region.

SKU:: B75-H5259
Additional Names:: B7-H5|Gi24|SISP1|VISTA
Physical State:: Powder
Molecular Weight:: 44.8 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: B7-H5
Species:: Human
Extra Details:: Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.