B74-H5256
Human B7-H4 Protein, Fc Tag, low endotoxin
Cannot supply to this region.
- SKU:
- B74-H5256
- Additional Names:
- B7-H4|B7h.5|B7S1|VTCN1
- Physical State:
- Powder
- Molecular Weight:
- 51.8 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- B7-H4
- Species:
- Human
- Uniprot:
- Q7Z7D3-1
- Synonyms:
- B7 homolog 4;B7h.5;Immune costimulatory protein B7-H4;Protein B7S1;T-cell costimulatory molecule B7x
- Extra Details:
- V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.
- Shipping Conditions:
- Ambient