Biotinylated Human B7-H3 (2Ig) / CD276 Protein, Avitag[TM],His Tag

Cannot supply to this region.

SKU:: B73-H82E6
Additional Names:: B7 homolog 3|B7-H3|CD276
Physical State:: Powder
Molecular Weight:: 26.5 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: B7-H3 (2Ig)
Species:: Human
Uniprot:: Q5ZPR3-2
Synonyms:: 4Ig-B7-H3;B7 homolog 3;Costimulatory molecule
Extra Details:: B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.