AXL-H5253
Human Axl Protein, Fc Tag (MALS verified)
Cannot supply to this region.
- SKU:
- AXL-H5253
- Additional Names:
- AXL|UFO
- Physical State:
- Powder
- Molecular Weight:
- 72.6 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 100 mM Glycine, 150 mM NaCl, 25 mM Arginine, pH7.5
- Immunogen:
- Axl
- Species:
- Human
- Uniprot:
- P30530-1
- Synonyms:
- AXL oncogene
- Extra Details:
- AXL Receptor Tyrosine Kinase is also known as Tyrosine-protein kinase receptor UFO, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. AXL contains two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. AXL is highly expressed in metastatic colon tumors. AXL is activated by GAS6-binding and subsequent autophosphorylation. AXL is involved in signal transduction from the extracellular matrix into the cytoplasm by binding growth factors, and thus implicated in the stimulation of cell proliferation.
- Shipping Conditions:
- Ambient