Mouse ASGR1 Protein, His Tag, low endotoxin (MALS verified)

Cannot supply to this region.

SKU:: AS1-M5243
Physical State:: Powder
Molecular Weight:: 27.7 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 0.2 M Arginine, PBS, pH7.4
Immunogen:: ASGR1
Species:: Mouse
Uniprot:: P34927
Synonyms:: A;AS;Asg;ASGPR1;Asgr;Asgr-1;asialoglycoprotein receptor 1;hepatic lectin 1;HL-1
Extra Details:: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]