APP-M52H3
Mouse APP / N-APP Protein, His Tag (MALS verified)
Cannot supply to this region.
- SKU:
- APP-M52H3
- Additional Names:
- ABPP|Amyloid-beta A4 protein|APPI
- Physical State:
- Powder
- Molecular Weight:
- 31.9 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- APP
- Species:
- Mouse
- Uniprot:
- P12023-1
- Synonyms:
- ABPP;Alzheimer disease amyloid A4 protein homolog;Amyloid precursor protein;Amyloid-beta precursor protein;Amyloidogenic glycoprotein
- Extra Details:
- Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. The majority of APP is cleaved at the plasma membrane by the A Alpha-secretase in the non-amyloidogenic pathway. The amyloidogenic pathway starts with B Beta-secretase cleavage by BACE1 on the N-terminal part of the AB Beta domain, releasing sAPPB Beta from a membrane-anchored fragment named B BetaCTF or C102, which is subsequently cleaved by G Gamma-secretase to release AB Beta.
- Shipping Conditions:
- Ambient