Human APRIL / TNFSF13 Protein, Fc Tag, low endotoxin

Cannot supply to this region.

SKU:: APL-H5263
Physical State:: Powder
Molecular Weight:: 42.2 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS, 0.5 M Arginine, pH7.4
Immunogen:: APRIL
Species:: Human
Uniprot:: O75888-1
Synonyms:: A proliferation-inducing ligand;TNF- and APOL-related leukocyte expressed ligand 2;TNF-related death ligand 1
Extra Details:: APRIL(a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFSF13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.