Mouse ALPL Protein, His Tag (active enzyme, MALS verified)

Cannot supply to this region.

SKU:: ALL-M52H3
Physical State:: Liquid
Molecular Weight:: 55.5 kDa
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 20 mM Tris, 150 mM NaCl, pH7.5
Immunogen:: ALPL
Species:: Mouse
Uniprot:: P09242
Synonyms:: Ak;Akp;Akp-2;Akp2;Alkaline phosphatase 2;alkaline phosphatase 2, liver;Alkaline phosphatase liver/bone/kidney isozyme;alkaline phosphatase, tissue-nonspecific isozyme;ALP;APTNAP;T;TNAP;TNSALP
Extra Details:: This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.