ACA-H5269
Human / Cynomolgus Activin RIIA / ACVR2A Protein, Fc Tag
Cannot supply to this region.
- SKU:
- ACA-H5269
- Additional Names:
- Activin receptor type IIA|ACTRIIA
- Physical State:
- Powder
- Molecular Weight:
- 39.9 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
- Immunogen:
- Activin RIIA
- Species:
- Human, Non-human Primate
- Uniprot:
- P27037-1
- Synonyms:
- Activin receptor type IIA
- Extra Details:
- Activin receptor type-2A (ACVR2A) is also known as Activin receptor type IIA, ACTR-IIA, ACTRIIA and ACVR2,which is single-pass type I membrane protein. ACVR2A belongs to the protein kinase superfamily,TKL Ser/Thr protein kinase family and TGFB receptor subfamily.On ligand binding,ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.ACVR2A is Receptor for activin A, activin B and inhibin A as well. Several type I I activin receptors have been identified and bind to different activins with different affinities.
- Shipping Conditions:
- Ambient