5HR-H55D3
Human 5-HT2AR Protein (S162K, M164W, S372N), Flag,His Tag (Detergent)
Cannot supply to this region.
- SKU:
- 5HR-H55D3
- Physical State:
- Liquid
- Molecular Weight:
- 55.3 kda
- Storage Conditions:
- -70[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM HEPES, 150 mM NaCl, Buffer B, pH7.5
- Immunogen:
- 5-HT2AR
- Species:
- Human
- Uniprot:
- P28223-1
- Synonyms:
- Serotonin receptor 2A
- Extra Details:
- This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Dry Ice