37-1033
Human EGFR / HER1 / ErbB1 Recombinant Protein (Fc Tag)
Size
£578.00
- SKU:
- 37-1033
- Additional Names:
- ERBB Protein; ERBB1 Protein; HER1 Protein; mENA Protein; NISBD2 Protein; PIG61 Protein;
- Purification:
- > 97 % as determined by SDS-PAGE
- Storage Conditions:
- Store it under sterile conditions at -20[o]C to -80[o]C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
- Supplier:
- Abeomics Inc.
- Reactivities:
- Human
- Extra Details:
- Source : HEK293 Cells As a member of the epidermal growth factor receptor (EGFR) family; EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF; amphiregulin; TGF-alpha; betacellulin; etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation; survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization; the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK; PI3K/PKB and STAT). In addition; EGFR signaling also has been shown to exert action on carcinogenesis and disease progression; and thus EGFR protein is proposed as a target for cancer therapy currently. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy