36-3827
Recombinant Monoclonal Antibody to TRIM29 (Lung Squamous Cell Carcinoma Marker)(Clone : TRIM29/9256R)
Size
£397.00
- SKU:
- 36-3827
- Additional Names:
- Tripartite motif-containing protein 29, Ataxia telangiectasia group D-associated protein, Ataxia telangiectasia group D complementing gene (ATDC); Tripartite motif-containing protein 29 (TRIM29);
- Application:
- WB, IHC-Fr
- Purification:
- Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Supplier:
- Abeomics Inc.
- Host:
- Rabbit
- Reactivities:
- Human
- Clone:
- TRIM29/9256R
- Uniprot:
- Q14134
- Gene Details:
- TRIM29
- Extra Details:
- It recognizes a 66kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.