PerCP-Cy5.5 conjugated Anti-CD34 Monoclonal Antibody (Clone: 581)

Size

£842.00

SKU:: 30-1470PC-Cy5.5
Purification:: Purified antibody is conjugated with activated tandem dye of activated Peridinin-Chlorophyll Protein-Cyanine 5.5 (PerCP-Cy5.5) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Storage Conditions:: Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
Supplier:: Abeomics Inc.
Host:: Mouse
Reactivities:: Human
Extra Details:: CD34 is a highly glycosylated monomeric 111-115 kDa surface protein; which is present on many stem cell populations. It is a well established stem cell marker; though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion; differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions. Specificity: The mouse monoclonal antibody 581 reacts with an extracellular epitope of CD34; a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells; it is gradually lost on progenitor cells. The antibody recognizes the class III CD34 epitope resistant to neuraminidase; chymopapain and glycoprotease.

Shipping Conditions:: Blue Ice