Polyclonal Antibody to AP3 Delta

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£319.00

SKU:: 11-8086
Additional Names:: AP3D1||PRO0039
Purification:: Protein A Chromatography
Supplier:: Abeomics Inc.
Host:: Rabbit
Reactivities:: Human
Uniprot:: O14617
Gene Details:: AP3D1
Extra Details:: AP3D1 (AP-3 complex subunit delta-1) encodes the delta 1 subunit of an adaptor protein regulating intracellular vesicle-mediated transport (19631730). Lack of expression of functional AP-3, leads to a deficiency in vesicle transport and storage, which affects neurotransmitter vesicle turnover and release in the central nervous system (19032734). The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and directly involved in trafficking to lysosomes. It is implicated in intracellular biogenesis and trafficking of pigment granules and possibly platelet dense granules and neurotransmitter vesicles.