Polyclonal Antibody to Hes7

Size

£319.00

SKU:: 11-8084
Additional Names:: HES7||BHLHB37
Purification:: Protein A Chromatography
Supplier:: Abeomics Inc.
Host:: Rabbit
Reactivities:: Human
Uniprot:: Q9BYE0
Gene Details:: HES7
Extra Details:: HES7 (Hes family bHLH transcription factor 7) is a member of the Hairy-and-enhancer-of-split (HES) family of transcription factors, which play a role in somite formation. This is expressed in an oscillatory manner during the process of somitogenesis, a process by which somites (bilaterally paired blocks of mesoderm) form and give rise to skeletal muscle, cartilage, tendons, endothelial cells, and dermis. Missense mutations of HES7 have been reported to cause SCDO4 (Spondylocostal Dysostosis 4), an inherited disorder that is characterized by the presence of extensive hemivertebrae, truncal shortening and abnormally aligned ribs.