Polyclonal Antibody to ASAP2

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£319.00

SKU:: 11-8068
Additional Names:: ASAP2||DDEF2||KIAA0400
Purification:: Protein A Chromatography
Supplier:: Abeomics Inc.
Host:: Rabbit
Reactivities:: Human
Uniprot:: O43150
Gene Details:: ASAP2
Extra Details:: ASAP2 (Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2) or Development and differentiation-enhancing factor 2 (DDEF2) or Paxillin-associated protein with ARF GAP activity 3 (PAG3) is a multidomain protein containing two ANK repeats, one Arf-GAP domain, one PH domain and one SH3 domain. ASAP2 has two isoforms: PAPalpha and PAPbeta (111 and 106 kDa respectively) and both the isoforms are generally located in Golgi plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). ASAP2 regulates ARF-mediated vesicle budding when vesicular transport. ASAP2 has high level of expression in brain, kidney, and heart.