Polyclonal Antibody to Exportin-4

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£319.00

SKU:: 11-8014
Additional Names:: XPO4||KIAA1721
Purification:: Protein A Chromatography
Supplier:: Abeomics Inc.
Host:: Rabbit
Reactivities:: Human
Uniprot:: Q9C0E2
Gene Details:: XPO4
Extra Details:: Exportin-4 or XPO4 belongs to a large family of nucleoproteins that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments. Exportin-4 is a RanGTP-binding protein and functions as a receptor for nuclear export of EIF-5A and also may have a role as an adapter in RNA export. Exportin-4 has been reported to be involved in nuclear export of Smad3 and thereby regulation of Smad signaling. Diseases associated with XPO4 include pinguecula. This protein has ubiquitously expressed.