Polyclonal Antibody to Tis7

Size

£319.00

SKU:: 11-4016
Additional Names:: IFRD1
Purification:: Protein A Chromatography
Supplier:: Abeomics Inc.
Host:: Rabbit
Reactivities:: Human
Uniprot:: O00458
Gene Details:: IFRD1
Extra Details:: Tis7/IFRD1 (interferon-related developmental regulator 1) is expressed by neutrophils as a key modifier gene in cystic fibrosis (CF) lung disease. It functions as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. In skeletal muscle cells, Tis7 is known to function as a coactivator of MyoD by promoting the transcriptional activity of myocyte enhancer factor 2C (MEF2C). Mutations in Tis7 are associated with sensory/motor neuropathy with ataxia.