11-3030
Polyclonal Antibody to Viperin
Size
£319.00
- SKU:
- 11-3030
- Additional Names:
- RSAD2||CIG5
- Purification:
- Protein A Chromatography
- Supplier:
- Abeomics Inc.
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Uniprot:
- Q8WXG1
- Gene Details:
- RSAD2
- Extra Details:
- Radical S-adenosyl methionine domain-containing protein 2 is commonly known as Viperin consisting of 43 kDa protein. which is a interferon inducible viral protein. Viperin expression is induced by IFNα, IFNb, IFNg, human cytomegalovirus (HCMV) envelope protein, glycoprotein B (gB), etc. Viperin interaction with the viral protein vMIA results in viperin relocalization from the endoplasmic reticulum to the mitochondria. It interacts with the mitochondrial trifunctional protein which mediates beta-oxidation of fatty acids to generate ATP. Viperin promotes TLR7 and TLR9-dependent production of IFN-beta and also plays an important role in CD4+ T-cell activation and differentiation. Viperin is highly expressed in mouse and human brain.
- Shipping Conditions:
- Blue Ice