Polyclonal Antibody to Otx2

Size

£319.00

SKU:: 11-12025
Additional Names:: OTX2
Purification:: Protein A Chromatography
Supplier:: Abeomics Inc.
Host:: Rabbit
Reactivities:: Human
Uniprot:: P32243
Gene Details:: OTX2
Extra Details:: Otx2 encodes a transcription factor that plays a critical role in craniofacial development and anterior brain morphogenesis. Otx2 homologs in model organisms are expressed in a complex spatial, temporal, and gradient-specific manner that is required for correct antero-posterior patterning and craniofacial development. Otx2 mutations are associated with severe ocular phenotypes and central nervous system abnormalities such as seizures, short stature and developmental delay, CPHD (Combined Pituitary Hormone Deficiency), structural abnormalities of the pituitary gland and early onset retinal dystrophy.