Polyclonal Antibody to CD133/Prominin-1

Size

£319.00

SKU:: 11-10007
Additional Names:: PROM1||PROML1||MSTP061
Purification:: Protein A Chromatography
Supplier:: Abeomics Inc.
Host:: Rabbit
Reactivities:: Human
Uniprot:: O43490
Gene Details:: PROM1
Extra Details:: CD133/Prominin-1 is a pentaspan transmembrane protein that has been frequently used as a biomarker for cancer stem cells, although its biological function is unclear. CD133 is not restricted to somatic stem cells and cancer stem cells. It is expressed in differentiated epithelial cells in various organs. Due to the highly restricted expression of CD133 family molecules on plasma membrane protrusions of epithelial and other cell types, in association with membrane cholesterol, a role in the organization of plasma membrane topology has also recently been assigned to this family.