Mouse Monoclonal Antibody To N-Cadherin (Clone: 8C11)

Size

£319.00

SKU:: 10-7653
Purification:: Affinity Chromatography
Supplier:: Abeomics Inc.
Host:: Mouse
Reactivities:: Human, Mouse
Clone:: 8C11
Uniprot:: P19022
Gene Details:: CDH2
Extra Details:: N-cadherin(CD325) is a 140 kD protein belongs to a transmembrane molecules that mediate calcium dependent intracellular adhesion. Its extracellular region consists of five EC domains and has one cytoplasmic domain. N-cadherin is involved in organogenesis and maintenance of organ architecture by contributing to the sorting of heterogeneous cell types and in the cell adhesion needed to form tissues. N-cadherin is expressed by stem cells, myeloblasts, endothelial cells, and fibroblasts, and also is expressed in neural and muscle tissues and some types of carcinoma cells. CD325 associates with the cytoskeleton trough catenin proteins.