Monoclonal Antibody to Villin (Clone: ABM4E64)

Size

£319.00

SKU:: 10-7571
Additional Names:: VIL1||VIL
Purification:: Protein G Chromatography
Supplier:: Abeomics Inc.
Host:: Mouse
Reactivities:: Human
Clone:: ABM4E64
Uniprot:: P09327
Gene Details:: VIL1
Extra Details:: Villin is a protein that belongs to the gelsolin family of calcium-regulated actin-binding proteins. It is expressed in differentiated epithelial cells with a brush border such as intestinal villi, proximal renal tubules, oviduct, and seminiferous ducts. Villin shares structural and functional homology with two conserved families of proteins. One family of proteins, which includes gelsolin and adseverin, shares the conserved domain(s) found in the villin core. Villin regulates cell migration, cell death, and epithelial-to-mesenchymal transition underscoring the significance of this protein to epithelial cell function.