Monoclonal Antibody to Endoglin (Clone: ABM46D3)

Size

£319.00

SKU:: 10-7570
Additional Names:: ENG||END
Purification:: Protein G Chromatography
Supplier:: Abeomics Inc.
Host:: Mouse
Reactivities:: Human
Clone:: ABM46D3
Uniprot:: P17813
Gene Details:: ENG
Extra Details:: ENG (Endoglin) is an integral membrane glycoprotein that serves as a co receptor for members of the transforming growth factor-beta superfamily of proteins. It is a type I membrane glycoprotein expressed as a disulfide-linked homodimer on human vascular endothelial cells and is implicated in a dominant vascular dysplasia known as hereditary hemorrhagic telangiectasia as well as in preeclampsia. Endoglin suppresses human prostate cancer (PCa) cell invasion. It has been identified as a candidate tumor-suppressor gene in esophageal squamous cell carcinoma (ESCC).