10-4802
Monoclonal Antibody to Mouse CD137(Clone: 3H3)-NALE
Size
£375.00
- SKU:
- 10-4802
- Additional Names:
- Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, T-cell antigen 4-1BB
- Purification:
- Protein A/G
- Supplier:
- Abeomics Inc.
- Host:
- Rat
- Reactivities:
- Mouse
- Clone:
- 3H3
- Uniprot:
- P20334
- Gene Details:
- Tnfrsf9
- Extra Details:
- 4-1BB (CD137) is a costimulatory molecule expressed on the surface of activated T cells and plays a role in T-cell-mediated proliferative response. 4-1BB signal regulates CD28 co-stimulation in the targeted subset cells to favor Th1 development and maintain long-term cell growth. 4-1BB is also expressed on dendritic cells (DCs) and controls the duration, DC-T interaction, and, therefore, immunogenicity. Clone 3H3 antibody is an agonistic antibody that has been shown to stimulate 4-1BB signaling in vivo.
- Shipping Conditions:
- Blue Ice