Monoclonal Antibody to Mouse CD3 (Clone: 145-2C11)

Size

£319.00

SKU:: 10-4123
Additional Names:: T-cell surface glycoprotein CD3 zeta chain||T-cell receptor T3 zeta chain||CD247
Purification:: Protein G Chromatography
Supplier:: Abeomics Inc.
Host:: Hamster
Reactivities:: Mouse
Clone:: 145-2C11
Uniprot:: P24161
Gene Details:: Cd247
Extra Details:: CD3 is one of the several invariant chains that the variable chains of TCR: Alpha beta or Gamma delta TCR contains, and which support surface TCR expression and transduce the TCR signal. CD3D, along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK).