Monoclonal Antibody to Mouse EBI3 (Clone: ABM2C40)

Size

£319.00

SKU:: 10-4021
Additional Names:: Ebi3||Il27b
Purification:: Protein G Chromatography
Supplier:: Abeomics Inc.
Host:: Rat
Reactivities:: Mouse
Clone:: ABM2C40
Uniprot:: O35228
Gene Details:: Ebi3
Extra Details:: Epstein-Barr Virus Induced Gene 3 (EBI3) is an immune regulator that has been associated with the pathogenesis of inflammatory bowel disease. EBI3, as part of the immunosuppressive IL-35 cytokine, plays an important role in the regulation of intestinal immune responses by controlling overwhelming T-cell activation. EBI3 deficiency does not lead to changes in intestinal pathology in trinitrobenzene sulfonic acid colitis, but is protective in oxazolone-induced colitis.