Monoclonal Antibody to TLR7 (Clone: ABM2C27)

Size

£319.00

SKU:: 10-3015
Additional Names:: TLR7||UNQ248/PRO285
Purification:: Protein G Chromatography
Supplier:: Abeomics Inc.
Host:: Mouse
Reactivities:: Human
Clone:: ABM2C27
Uniprot:: Q9NYK1
Gene Details:: TLR7
Extra Details:: TLR7 (Toll-like receptor 7) is a member of the Toll-like receptor (TLR) family. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA; which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 controls host immune response against pathogens through recognition of molecular patterns specific to microorganisims. TLR7 interacts with MYD88 via their respective TIR domains and also interacts with UNC93B1. Post-translational modifications and glycosylation occur in TLR7. TLR7 detected in brain, placenta, spleen, stomach, small intestine, lungs and plasmacytoid pre-dendritic cells.