Monoclonal Antibody to TLR8/CD288 (Clone: ABM15F6)

Size

£319.00

SKU:: 10-3005
Additional Names:: TLR8||UNQ249/PRO286
Purification:: Protein G Chromatography
Supplier:: Abeomics Inc.
Host:: Mouse
Reactivities:: Human
Clone:: ABM15F6
Uniprot:: Q9NR97
Gene Details:: TLR8
Extra Details:: Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes.