YR0116
Human CD80 Monoclonal Antibody
Size
£486.00
- SKU:
- YR0116
- Additional Names:
- B7|B7-1|B7.1|BB1|CD28LG|CD28LG1|LAB7
- Application:
- ELISA, FuncS, Neutralisation
- Molecular Weight:
- 150 kDa
- Purity:
- >95%
- Storage Conditions:
- 2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Human CD80
- Formulation:
- Purified from cell culture supernatant in an animal-free facility
- Uniprot:
- P33681
- Synonyms:
- activation B7-1 antigen;B-lymphocyte activation antigen B7;B7;B7-1;B7.1;BB1;CD28LG;CD28LG1;CD80 antigen (CD28 antigen ligand 1, B7-1 antigen);costimulatory factor CD80;costimulatory molecule variant IgV-CD80;CTLA-4 counter-receptor B7.1;LAB7;T-lymphocyte activation antigen CD80
- Extra Details:
- A humanized IgG1 monoclonal antibody directed against CD80, the natural ligand for the T-cell antigen CD28 which mediates T-cell and B-cell adhesion. Galiximab binds to CD80 expressed on the cell surfaces of follicular lymphomas, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC). CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes and is often expressed at low levels on the surfaces of follicular lymphoma cells and other lymphoid malignancies.Galiximab, an IgG(1) anti-CD80 antibody, binds to CD80, a costimulatory molecule involved in T-cell activation. Reduction in lesional, activated T cells induces improvement in psoriatic plaques.
- Shipping Conditions:
- Blue Ice