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YR0012

Human CD52 Monoclonal Antibody

Size

£355.00

SKU:
YR0012
Additional Names:
CDW52|EDDM5|HE5
Application:
ELISA, FuncS, Neutralisation
Molecular Weight:
150 kDa
Purity:
>95%
Storage Conditions:
2-8[o]C Avoid freeze/thaw cycles., -70[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Immunogen:
Human CD52
Formulation:
Purified from cell culture supernatant in an animal-free facility
Uniprot:
P31358
Synonyms:
cambridge pathology 1 antigen;CAMPATH-1 antigen;CD52 antigen (CAMPATH-1 antigen);CDW52;CDW52 antigen (CAMPATH-1 antigen);EDDM5;epididymal secretory protein E5;epididymis secretory sperm binding protein Li 171mP;HE5;HEL-S-171mP;human epididymis-specific protein 5
Extra Details:
Alemtuzumab is a medication used to treat chronic lymphocytic leukemia (CLL) and multiple sclerosis. In CLL, it has been used as both a first line and second line treatment. In MS it is generally only recommended if other treatments have not worked. It is given by injection into a vein.It is a monoclonal antibody that binds to CD52, a protein present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes are derived. After treatment with alemtuzumab, these CD52-bearing lymphocytes are targeted for destruction.
Shipping Conditions:
Blue Ice