RP03531
Recombinant Mouse SFRP1 Protein
Size
£574.00
- SKU:
- RP03531
- Additional Names:
- Sfrp1,Secreted frizzled-related protein 1, sFRP-1
- Molecular Weight:
- 35-45 kDa
- Purity:
- ≥95%
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Met1-Lys314
- Formulation:
- Recombinant Mouse SFRP1 Protein is produced by CHO Stable Cells expression system. The target protein is expressed with sequence (Met1-Lys314) of Mouse SFRP1 (Accession # Q8C4U3) fused with His tag at the C-terminus.
- Species:
- Mouse
- Uniprot:
- Q8C4U3
- Synonyms:
- 2210415K03Rik;AW011917;AW107218;AW742929;secreted frizzled-related protein 1;secreted frizzled-related sequence protein 1;sFR;sFRP-1
- Extra Details:
- Mouse sFRP1 is highly expressed in kidney and embryonic heart, as well as in the eye, where it is principally localized to the ciliary body and the lens epithelium.Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels.Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase. In kidney development, inhibits tubule formation and bud growth in metanephroi.
- Shipping Conditions:
- Blue Ice