RP03521
Recombinant Human IL-35/IL-12A&IL-27B Protein
Size
£645.00
- SKU:
- RP03521
- Additional Names:
- IL-35, IL-12A&IL-27B, IL12A, NKSF1&EBI3, IL27B,IL35,IL 35
- Molecular Weight:
- 60 , 63 KDa
- Purity:
- ≥90%
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Met1-Ser219 & Met1-Lys229
- Formulation:
- Recombinant Human IL-35/IL-12A&IL-27B Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ser219) of IL-12A fused with a C-terminal Fc region of human IgG1 tag followed by a His tag and sequence (Met1-Lys229) of IL-27B was fused with a C-terminal Fc region of human IgG1 tag followed by a FLAG tag,The two plasmids were co-expressed and the heterodimer was purified.
- Species:
- Human
- Uniprot:
- P29459-1, Q14213
- Synonyms:
- CLMF;CLMF p35;cytokine receptor;cytotoxic lymphocyte maturation factor 1, p35;cytotoxic lymphocyte maturation factor 35 kDa subunit;EBV-induced gene 3 protein;Epstein-Barr virus induced gene 3;epstein-Barr virus-induced gene 3 protein;IL-12 subunit p35;IL-12, subunit p35;IL-12A;IL-27 subunit beta;IL-27B;IL27 subunit;IL27B;IL35 subunit;IL35B;interleukin 12, p35;interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35);interleukin-12 alpha chain;interleukin-12 subunit alpha;interleukin-27 subunit beta;NF cell stimulatory factor chain 1;NFSK;NK cell stimulatory factor chain 1;NKSF1;P35
- Extra Details:
- IL-12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. IL-12A, together with IL27B, form a disulfide-linked heterodimer: IL-12A&IL-27B. IL-12A&IL-27B is required for the T-cell-independent induction of IFN-gamma and is important for the differentiation of both Th1 and Th2 cells.
- Shipping Conditions:
- Blue Ice